Chapter 1613

Qi Kai didn't seriously consider Chen Cang's words before!

If other laymen ask, they will even feel childish and ridiculous.

Because doesn't a disease have these various comprehensive manifestations?

But!

Today is different!

Who is Chen Cang? This is a new star in the field of neurosurgery and the pillar of the future of Chinese medicine!

Otherwise, would Xiao Runfang give it to such a big crowd?

What do you mean regardless of cost and full cooperation!

When Qi Kai heard Chen Cang's words, he began to think back and ponder!

Can static tremor, myotonia, bradykinesia, etc. be modeled separately?

What is the meaning of separation?

Thinking of this, Qi Kai looked at Chen Cang and asked curiously, "Professor Chen, do you think it is of great significance to make models separately?"

Chen Cang nodded!

He is a person who has thousands of clinical experience in human Parkinson's surgery.

He clearly remembers that the production of Parkinson's lesion is definitely not a simple place.

It is necessary to select different areas to establish damage foci.

It is also the target selection of Parkinson's disease.

The ventrolateral thalamic nucleus is effective in tremor and stiffness, but its effect on motor retardation is uncertain.

The medial part of globus pallidus is effective for stiffness and bradykinesia, followed by tremor!

Similarly, they are the ventral intermediate nucleus of thalamus. Chen Cang needs surgery to make the specific location of the lesion is also different!

Hearing Qi Kai's words, Chen Cang nodded and said, "well, it's different!"

"When I was doing patient surgery, director Zhou Hongguang himself was a Parkinson's manifestation of both hands static tremor. What I chose was the ventromedial nucleus of thalamus, and the operation effect was obvious!"

"So, I guess, can we establish some rat models?"

Hearing Chen Cang's words, Qi Kai suddenly came to light: "Professor Chen's ideas are very constructive!"

"Let's go. There's my studio ahead. Let's come in and have a look!"

Chen Cang nodded with a little excitement and expectation.

……

……

After Qi Kai put on his clothes, he said to Chen Cang, "our modeling process is actually based on medical knowledge!"

"It is mainly based on the pathological features: the loss of dopaminergic neurons in substantia nigra and the emergence of Lewy body, an inclusion body in the cytoplasm."

"These combined effects lead to the occurrence of Parkinson's disease, which is actually a result: the balance of acetylcholine and dopamine is unbalanced, which is caused by the increase of acetylcholine and the decrease of dopamine."

Chen Cang nodded.

Chen Cang understands this pathological state.

At present, the main treatment is dopamine drugs, or inhibit the secretion of acetylcholine, forming a new balance.

But

The effect is worrying!

Qi Kai introduced it in detail while operating.

"In fact, this instrument mainly measures dopamine."

"The number and shape of dopaminergic neurons are normal at birth. They begin to decrease selectively in youth. When the reduction reaches 50%, various reactions can occur. Moreover, this number can be detected by neurochemical and neurophysiological methods. You see... This is it!"

"This model can show the formation of Louis corpuscle."

"By the way, we can detect heredity!"

"This thing is our unique skill. Foreigners don't even have such technology in the United States!"

……

When introducing the instruments and achievements, Qi Kai was very excited and proud!

This is his lifelong pursuit.

When making the mold, Qi Kai was very serious.

The students on one side will help him again.

Qi Kai didn't work very hard.

The little mouse had been anesthetized and lay on it for slaughter. He should be very happy to think that as long as he slept, he would be a noble Parkinson's rat when he got up in the morning.

After all, the value has increased hundreds of times!

It's a pity.

It can't decide this by itself.

"Now we mainly use hexahydroxydopamine by injecting it into the substantia nigra or medial forebrain tract of rats," Qi Kai said

"This is a classic preparation method!"

While talking, the operation began.

After that, he continued, "there is another method, which has been developed in recent years, called MPTP tube feeding."

One afternoon, Chen Cang witnessed several modeling methods!

Director Qi Kai is knowledgeable!

He told Chen Cang a lot about the structure, physiology and pathology of rats.

It can be said that it has benefited a lot!

Just as Chen Cang was about to leave, Chen Cang was surprised to find:

My progress bar has been improved by 1 point!

Although there is only one point.

But this is enough to surprise Chen Cang.

[progress bar: 28%!]

With the harvest, Chen Cang was pleasantly surprised!

The next day, Chen Cang continued to come!

Also, add 1 point!

For several days in succession, Chen Cang himself has been able to make simple molds!

Chen Cang's butcher's knife finally reached the rat!

At this moment, the rat fell down peacefully.

But

Accompanied by a crisp prompt sound.

Chen Cang was pleasantly surprised.

Your 30 progress bar has been reached!

[Ding! Congratulations, Parkinson's progress bar reaches 30%, and you will be rewarded: Stereotactic precision injection modeling method!]

Accompanied by a prompt sound.

Chen Cang was stunned!

Make... Make... Mold!?

Me and him

This is not what I want at all.

Chen Cang wants to cry without tears.

I want to save people.

It's not a mouse!

But

When Chen Cang finished reading this technology completely, Chen Cang was stunned directly!

This is both an accurate method of animal modeling.

It is also a therapeutic method of the human body!

This is a means of simultaneous internal and external science.

For modeling, it is a method of stereotactic injection of MPTP (a complex compound, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) into the brain by using stereotactic technology.

Chen Cang was surprised when he learned.

Maybe... It can not only make models for animals, but also for people?!

As usual, facing director Qi, Chen Cang asked curiously, "director Qi, what would happen if we studied directional, simple rat models such as static tremor, simple myotonia, or simple imbalance?"

Qi Kai couldn't help laughing and said, "this... Is great!"

"This is the core technology!"

"If we realize that technology, our research on Parkinson's will be upgraded to a higher level!"

"It will even directly accelerate the research on Parkinson's disease!"

"This is a historic project. After you said that day, I went back to study it. It's not impossible, but... It's too difficult!"

Chen Cang smiled: "director Qi, look at my mice. They may all be static tremors. Do you believe it?"

……

PS: thanks for the 10000 reward from the leader of Guoguo alliance, thank you!

Send it at five o'clock and ask for a monthly ticket.