Chapter 1770

Chencang Institute of new drugs, Dongyang high tech Development Zone.

It has been officially put into operation for several months. Everyone is working hard on scientific research and hopes to conquer Parkinson's disease as soon as possible.

After Chen Cang put forward the similarities between Alzheimer's disease and Parkinson's disease, the progress of the whole scientific research work has been greatly improved!

However, scientific research always gives people an illusion!

That is, every breakthrough makes people feel that it is a historic progress and that they can achieve excellent results.

But the result is... After every breakthrough, I suddenly find that this thing is more difficult!

To solve problems, the factors and disciplines that need to be considered and studied are still increasing!

Professor Zhang Mu himself is engaged in the research of Alzheimer's disease, so when Chen Cang proposed that asparagine endopeptidase enzymes can modify tau protein to make it more viscous and toxic.

Therefore, drugs that inhibit AEP often show certain benefits in the treatment of animal models of Alzheimer's disease.

In this way, is there an enzyme that can increase folding α- What about the toxicity of synuclein?

This problem is really complicated!

It even feels like looking for a needle in a haystack.

No one can find an "enzyme" from complex tissue to show that this thing is pathological after folding α- Does synuclein promote it?

This requires complex bioengineering to deal with!

There was a tense and anxious discussion in the office.

Tedanis frowned and said, "the progress of enzyme engineering is too slow. So far, I haven't received an accurate answer from Professor kangxidin!"

"Every time I talk about cooperation, the other party is looking for all kinds of reasons to prevaricate."

"Hey..."

Hearing that tedanis was so lost, everyone didn't know how to comfort.

Kangxiding and tedanis used to be good partners.

But since tedanis came to China, his reputation has been like a crooked ass in a certain circle, and everyone has avoided it one after another.

To tell the truth, scientific research is divided into national boundaries most of the time.

Even if many people are unwilling to admit it, they will find all kinds of reasons to convince themselves and others.

For example, Chen Cang is indeed the fastest person in the field of Parkinson's research, but why are those powerful experts unwilling to join?

Is it because they are stupid and don't understand?

Of course not!

It's not that you're good, everyone will join you.

A very realistic problem is that scientific research is always like competition.

As long as you don't study the results, no matter how ahead you are, you can't be successful!

Now, for example, the institute needs experts in the field of enzyme engineering.

But this top expert is really hard to find.

A few of tedanis's former partners are now willing to come too little!

Domestic bioengineering itself is the initial stage, and the research on protein enzymes is really stretched.

Even the simplest enzyme separation and purification uses some biofilm separation technologies retired from the United States five years ago.

These are basic research!

However, these basic studies determine the superstructure.

No scientific research is produced out of thin air.

As the person in charge, Zhang Mu couldn't help sighing.

The development of domestic medicine is really not only the backwardness of pharmaceutical technology, but also because the development of medicine is a comprehensive discipline!

Medicine is not a simple subject, but a sophisticated subject.

It involves physics, chemistry, Molecular Biology... And many other basic disciplines!

Even the separation and purification of a small direction of enzyme engineering is very difficult at this moment!

For a moment, everyone was quiet.

Yang Lan couldn't help saying, "why don't we find an old friend of the Chinese Academy of Sciences?"

Zhang Mu shook his head: "his technology is similar to that of Yu Shuangyong. Don't look for it, and the effect is not obvious."

Yu Shuangyong blushed at this.

Although what Zhang Mu said is not very face saving, it is a real truth!

It has become a problem to find the key core of a small enzyme!

At this time, the door opened suddenly.

The people who were thinking were suddenly stunned, some stunned, and even startled. For a time, everyone was unhappy!

Who's here during the meeting?

Everyone turned around and found that it was Chen Cang!

Everyone was relieved.

Seeing that the atmosphere was somewhat depressed, Chen Cang couldn't help but be stunned: "what's the matter... Is this?"

"Is the atmosphere so depressing?"

Everyone sighed at the sound.

Zhang Mu said directly, "Professor Chen, I'm just going to find you. Sit down and say."

Chen Cang nodded, took a seat and looked at Zhang Mu: "what's the matter?"

Zhang Mu said to Yu Shuangyong, "Lao Yu, tell me about it."

Yu Shuangyong nodded and picked up the data in his hand:

"Well, we have extracted, separated and purified the enzymes in the rat nervous system. We want to study them according to Professor Chen's idea at the beginning."

Asparagine endopeptidase can modify the tau protein in aziam, which is more toxic and adhesive. As you said, Parkinson is the only neurodegenerative disease with a secondary incidence rate of Alzheimer's disease. We have also begun to isolate and purify the enzymes in Parkinson's rat.

"But... It seems that we have encountered some problems. I don't know whether it is due to technical reasons or other reasons. In this month, we have carried out more than 600 separations, more than 3000 tests and tens of thousands of tests, and found no enzyme that can fold α- Synuclein is more toxic! "

"This is the specific data. We can now find only 671 enzymes, which can no longer be carried out!"

After Yu Shuangyong finished, everyone sighed.

Tedanis couldn't help but say, "I found my friend Professor kangxidin, but... The other party didn't seem willing to help us!"

Zhang Mu suddenly suggested, "Professor Chen, why don't we... Change our direction?"

Everyone nodded.

Since there is no way to break through the asparagine endopeptidase of Alzheimer's disease in the field of enzymes, maybe we should change direction?

After all... Enzyme engineering is really expensive.

This month, according to Zhang Mu's statistics, he has invested nearly 30 million yuan in this field. He has nothing to gain. He has drifted away!

This is scientific research, cruel and realistic!

Just when everyone was a little lost.

Chen Cang suddenly said, "why don't... I'll try?"

As soon as he said this, everyone around him became quiet.