Chapter 68

"Zheng Jianguo is very glad that he chose the direction of Helicobacter pylori in the digestive system. Otherwise, he would have to follow Ye minde to catch mice. Of course, the one he chose also needs animal experiments, but that's what he has to do after finding Helicobacter pylori from his stomach. Now what he has to do is to find all the literature on stomach diseases——

In his memory, Zheng Jianguo picked up his mobile phone, casually opened a search bar, typed in the desired keywords, and just pressed enter to find all the Chinese content on the Internet. At present, if he had a mobile phone in his hand and could connect to the Internet, he would find that in 1892, 86 years ago, An Italian Bizzozero found spiral bacteria in the stomach of mammals.

Of course, this was found in the stomach of mammals. When it was found in the stomach of advanced mammals, in 1939, 47 years after Comrade Bizzozero's discovery, doenges observed 242 cases of stomach with hematoxylin eosin staining after autopsy. It was found that there were spirochete like microorganisms in 43% of the autopsied stomach.

Not to mention that most of the spirulina microorganisms found this time are located in the glandular cavity and a few in the range of parietal cells, but the discovery of doenges et al. Comes from the anatomy of human cadavers. Because human cadavers will have tissue autolysis after death, it is difficult to evaluate this Spirulina bacterium in gastropathology.

Not to mention the lack of food in the stomach of the corpse, even if Spirillum can survive for a short time to be stained after death, it can not continue to release enzymes to decompose urea into ammonia and carbon dioxide without the presence of urea in the food. Because this enzyme can decompose urea, it is called urease.

As there is water in the stomach at the same time as the food, the ammonia decomposed by urea will become a weak base. Therefore, the gastric mucosa, which looks like King Kong and is not bad in gastric acid, disintegrates in minutes. The consequence of the cessation of this series of chemical reactions is that doenges and others lose the opportunity to further understand Helicobacter.

Although there was no mobile phone available at this time, Zheng Jianguo did not know that Spirillum had been looming under the eyes of researchers for more than 100 years, but he knew that Spirillum survived in the stomach by urease, so dysentery, gentamicin and penicillin could have an immediate therapeutic effect.

So after receiving Ye minde's request to find relevant documents, Zheng Jianguo went to the library. After diving in for more than a month, he almost didn't come up at last——