There are many methods for drug testing in drug research and development, but they must be observed, including comparison, balance, randomization and repeatability.
There are many jokes here. For example, this is repetitive. When a university wanted to be upgraded, but the number of experiments was not enough, they opportunistically opened a Chinese Journal and began to copy it. Results the experiment was replicated, but the data could not reach repeatability at all.
As for the control, there is a classic experiment. In the early years, many leaders added trace elements, such as a leader of Jinmao added vitamins to supplementary foods. Another example is the selenium containing rice in China in recent years.
It's like if you don't eat this rice, you will be stunted and you won't have enough IQ.
In fact, this selenium experiment was carried out by scientists in the 1960s. A team of about 500 people was found. 250 experimenters added selenium especially. 250 people ate a normal diet without adding additional selenium.
As a result, the experiment was supposed to be done for 7 years, but it could not be done in the third year. There was no change in the control group. Whether to eat additional selenium enriched elements or not did not change at all. Why can't it go on? The boss who paid for it saw that the experiment can't be done. If it goes on, it's hard to boast in the future!
In fact, unless it needs to be added in some areas that are particularly short of selenium, there is no need to supplement it in normal areas, unless you have a lot of money and people are stupid.
For the TB drug experiment of tea element, there is no way to carry out double-blind experiment, so we can only choose the control experiment.
Thousands of TB patients need thousands of normal drug testing personnel. Tea element is congenitally deficient in this respect.
For example, in big cities, not to mention other bright and dark markets, first of all, a medical school can find many medical students. Tea is not good, because you are not a medical student. If you don't talk about science popularization first, it is easy to panic.
"Zhang Yuan, there are not enough people!" Lao Chen blocked Zhang Fan in the operating room. Lao Chen seldom entered the operating room, which was forced by a group of old men, so he killed him in the operating room.
"Do you think of a way? You are such a big Dean. Can't you even handle this matter?"
"My Dean, you can't let me start the army. This can't work. When we are ischemic, we look for the army. Even when the hospital moves, we look for the army, but this can't work."
"Hey!" Zhang Fan is sad. Although there are a lot of idle people on the tea vegetable street, it's really hard to find such a large number of drug testers.
First, we should be healthy. Second, we must be able to understand popular science. Third, we need to take some risks.
So it's hard.
Suddenly, Zhang Fan thought of a way, and then looked at Lao Chen with suspicious eyes. Lao Chen's innocent expression was like a fox who had to say he didn't steal a chicken.
The state has regulations on the treatment of drug testers. We must inform them of adverse drug reactions. Once there is an accident, the hospital must bear the treatment cost.
In addition to these, we have to give fixed funds, and subsidize nutrition, transportation and one-time expenses, which are about 1000 yuan.
Although many drugs have been tested by animals, there are still risks. Many big cities have drug heads that make money, just like group performance heads, they can form business.
We can't find anyone for tea. We can only rely on the government. To tell the truth, this thing can only be done by Zhang Fan or Ouyang. Others really can't take it down. No wonder Lao Chen pretends to be crazy.
After Zhang Fan changed his clothes, he drove to the tea vegetable government.
Under the blue sky, kuluze slipped into the door of the tea government like a fish, which was particularly conspicuous. If left in the past, Zhang Fan's car in the frontier government was too ordinary.
A leader is the king of the desert. Now he can't. kuluze has become a cheetah and the four circles have become a red flag. It's not easy to meet a sunny day, and it's better this year.
The boss of the government stood by the window, basking in the sun and looking at the factories allocated land, especially the modern enterprises on the other side of the high-tech zone, which made the leaders feel quite different. This is the river and mountain laid by Lao Tzu.
As a result, I saw Zhang Fan's kuluze in the corner of my eye. This car is so easy to recognize. This is the kuluze tea with a red card, and there are a row of passes from province to city and from city to county on the window. I don't know. I thought it was a United Nations car.
"It's bad. There must be no good. Whoever leaked the news of me, I was chased by someone when I entered the office. Be sure to find out who it is."
The boss of the government is very angry. He is not afraid to see Zhang Fan or Ouyang. He is afraid that Ouyang will ask for debt. It is said that the tea vegetable government went to the capital this time. Ouyang seems to have been personally commended by the general manager.
Nima used to be arrogant and unreasonable. Now it is estimated that NIMA is even more powerful.
"I don't think he came to ask for debt?" The director of the next office replied. After answering, he wanted to slap himself.
This thing is right. There is no reward. It's wrong. When Ouyang leaves, the boss estimates that he will vent his anger on his long mouth.
Hey!
After a while, boss Cha Su saw Zhang Fan's smiling face, and Zhang Fan was alone. The boss breathed a sigh of relief. He really didn't come to charge. If he came to charge, he wouldn't be Zhang Fan.
"Make tea for Zhang Yuan. Don't make green tea. Just Tie Guanyin. Zhang Yuan likes to drink it." Tea vegetable laughed and said to the office director. The office director greeted Zhang Fan with a smile. Really, he was like wearing a pair of angular Gauguin shoes on a grand occasion. He was painful at every step and had to put a thick smile on his face.
After making tea, Zhang Fan politely took out two gadgets from his handbag. "This is a gift to the leaders in the capital. It's not worth money. It's just a thought."
When Zhang Fan took out the gift, boss Cha Su's face turned white. It didn't mean that he was afraid of what a thick card Zhang Fan's gadget was, because he believed that Zhang Fan was telling the truth. Just because he believed the truth, he was afraid.
When did these two goods of tea vegetarians give gifts? They wanted to give them gifts by themselves. This guy is a rare gift today. It's definitely not a good thing.
The boss hurriedly pushed his hands. "We can't do anything valuable or worthless. We can't break the rules. No, No."
"Worthless, worthless!"
"Don't say it's worthless. Even if it's worth money, it's really not worth it."
They are like aunts on the street.
Finally, Zhang Fan still didn't take it out. Zhang Fan actually had a reason to speak. You want me to say it, but you don't want me to say it. Seeing that the leader was facing a great enemy, he put the souvenirs ordered from Xiangshan in his handbag.
Zhang Fan looked at the office director, meaning that the boss didn't want you to have one? The office director's face has changed. Let Zhang Fan drink tea.
Zhang Fan was not polite when he saw it.
At the moment of sitting down, Zhang Fan seemed to hear a sound:
Shh!
"After the meeting of the Committee of our tea vegetable hospital, we decided to pay dividends to relevant pharmaceutical enterprises at the end of next year. After all, this year is profitable."
As soon as I said this, if the dean of Su University Clinical College was there, he would jump to swear. You bastard, you stole the teacher.
As soon as the boss of tea vegetable heard that he wanted to pay dividends, he was happy, and then at the end of next year, his lost heart was broken.
"Can you make it a little earlier, for example, by the end of this year? After all, let's see if the contribution of tea vegetable hospital is not good."
Zhang Fan certainly won't promise to pay dividends this year. It is estimated that the dividends at the end of next year are to let the fish take the bait.
Zhang Fan looked embarrassed. "It's too late to pay dividends this year, but it's OK to advance a little, but it's estimated to be the middle of next year. It's difficult to pay dividends as early as possible."
"Hey!" Boss Cha Su knew at a glance that Zhang Fan didn't really want to pay dividends, so he didn't want to take over.
"If you don't give me benefits, don't want me to take over."
Zhang Fan looked at it and sighed in his heart, "Chinese talents are gathered in the system. That's true."
When the president said this, Zhang Fan was very upset, but this one in the opposite side has always been thinking about the law and asked Zhang Fan to implement it early. As for others, he won't take the bait at all.
"I wanted to pay dividends early, but..." Zhang Fan was interrupted halfway through.
The leader seems to suddenly think of something very important. He should get up and leave immediately.
"Director Yang, is there another important meeting? Why don't you let the room chief come and talk to Zhang Yuan!"
"This guy wants to run!"
Zhang Fan hurriedly said, "why don't you let the European Academy come?"
"It's not necessary, it's not necessary. There are a few minutes left. We'll hurry up. You're a big expert. The hospital can't do without you. I can't waste your time. Let's make a long story short."
The leader looked at it and frowned like a knife. He thought, "it's too difficult! Why is it so difficult."
"Well, the test personnel..."
Listening to Zhang Fan's words, the leader's face was green, red and white, and his hands trembled.
Don't I owe you some money? Are you such a bully?
"Those who give subsidies, those who give subsidies, 1000 yuan per round."
"Five thousand!"
"Er, let..." Zhang Fan wanted to ask Ouyang to talk, but he thought again that he couldn't always scare people with the European court. If he frightened the skin, people wouldn't be afraid.
"Leadership, five thousand is really not good. I'm in charge, one thousand one, no more!"
"Four thousand, or there's no need to talk about it. Your hospital is not under the leadership of tea vegetable now. Don't scare me. The government still owes hundreds of millions to the bank."
After struggling for a long time, seeing that Zhang Fanshi couldn't take it out, he pushed the price at fifteen. When he got out of the door, Zhang Fan got on the car singing.
To tell the truth, leaders are smart enough, but they are not only unfamiliar with the field of medical treatment, but also have little concept of money estimation.
After fooling the leaders with professional knowledge for the first time, Zhang Fan felt quite proud. Really, this sense of achievement is no less than the feeling of passing the practice examination.