Allogeneic transplantation with anti rejection gene is simply to induce the small pig skin and active pig skin by implanting various factors to make it look like the gene of human skin, and then plant it on the human body to make them perfectly combine with the human body.
In a word, Professor Li Housen and his team have been struggling for nearly ten years. When they came back from the United States, they began to study. He didn't perform the surgery as well as the Korean American brothers. However, his strength lies in research. Finally a little eyebrows, the results in the clinical promotion can not open, really, Lao Li's heart is broken.
"Small curette, syringe."
At the beginning of facial repair, Zhang Fan gently scraped the slightly white skin along the texture with a scraper again. He must first transplant his own mucosa and fat.
Scald is too hateful. It's not like chopping and chopping, but a very complex compound injury.
After removing the scalded tissue, the injured area is a lot of pits of different sizes, just like the ground bombed by shells on the battlefield, and so is the face of the wounded.
"Open your mouth." LV Shuyan used the mouth opener to open the patient's mouth without disorder. Zhang Fan has a syringe in his left hand and a scalpel in his right hand. While flushing, use the scalpel to start selecting materials along the oral cavity.
The face of the wounded was seriously damaged. Fortunately, the eyes and nose were preserved, but the lips were directly burned like rotten plastic.
If this place is not repaired, it will only be tighter and tighter in the future. Because the muscle texture around the mouth is a circle of circular muscles, in fact, it is a little rough. The structure of this place is similar to that of the anus. There is a ruddy lip.
To do the best is Zhang Fan's belief. The mucous membrane in the mouth is selected to create a new ruddy lip.
This mucosa must be provided by itself, and there are very few places to obtain materials. Only the oral cavity and Yin (a) tract can supply limited mucosa. Therefore, for male patients, it can only be successful at one time, otherwise there is no place to obtain materials.
"Hemostatic cotton." Zhang Fan cut off a rectangular mucosa with vascular pedicle in the buccal part of the mouth with a scalpel“ Needle holder, absorbable thread. " Suture the mouth.
"Baoyin, put the mucous membrane into the bending plate and pour in the physiological solution." Zhang Fan explained.
"OK."
After the mucous membrane is placed, it is followed by fat. The best place for fat transplantation is the abdominal fat. The fat in other places is too dense and easy to liquefy and necrosis. It's too easy to take fat. Open the skin and cut it with a scalpel. After cutting, suture it directly.
Repair first. In fact, it is simply to dig the east wall to make up the west wall. LV Shuyan is about to pinch her hands. The girl can't see fat now, especially this kind of fat meat with very fat abdomen.
After preparing the materials, Zhang Fan began to repair the crater like face and filled it with fat first. The fat transplantation is very strange. The fat taken from the abdomen will be absorbed in other places.
Moreover, the absorption is very strong. Like being eaten by the body, it can almost reach 30% of the filling volume. Therefore, when filling, you can't fill as much fat as much pit. You must adjust it to prevent future absorption. Without adjustment, there will be collapse after transplanting piglet skin. The bigger the pit, the worse the collapse.
Professor Li Housen and Professor Yan Dehua watched Zhang Fan carry out the operation in an orderly manner, and the heart originally mentioned was slightly put down.
Although they didn't speak, they looked at each other. The meaning is clear: "from the current technique, it's not a mallet!"
Fat transplantation has a liquefaction process. The larger the fat area is, the more serious the liquefaction is. Because the larger the area is, the more damaged fat cells are, so it's best to extract fat beads under a microscope. How big is this, 4-6mm. The first to use this is the Korean beauty industry.
Fill the pits with fat one by one. The face originally scratched by Zhang Fan seems to be stuck with the cream of the birthday cake, piece by piece. It's as like as two peas. They are all white and are all raised.
It's really like a person with a bloody face, and then pasted with a piece of birthday cake.
After filling, start covering the allogeneic skin. It's time to show technology, especially Professor Li Housen, who is almost holding his breath.
In the large conference room outside the operating room, a group of Northwest transplant recipients whispered. The leaders who had watched it left after reading it for a while. It was too boring to understand! There are only these experts left.
"Lao Chen, yes, you undergraduates in LAN city are so awesome. It's only a few years since graduation, so skillful. "
"Nonsense, what do you think."
"Shameless stuff, as if it were your student." The other party couldn't chat. The professor who spoke was a little angry and full of stomach Fei.
In fact, his tone is a little contemptuous of Lanshi. After all, he is closer to the south.
"It's OK. It depends on the next step. Any doctor in our department can do it." A director of the army hospital said to the air force doctor nearby.
"Yes!"
The pink and tender pigskin is estimated to be still a baby pigskin. It has been soaked in various potions and is a little swollen. It rolls together like a blistered Guodan skin.
"Alice pliers, four. Director, come and help me open it. LV Shuyan, come and open it slowly. Don't use too much force. " The pigskin with vascular pedicle is too thin. If you exert too much force, it may be broken.
When he opened the pigskin, Professor Li Housen's heart almost jumped out of his throat. If you can't do this step well, you don't have to expect anything, and you won't do anything later.
The three men are even, "come on, slowly down, come on, slow, not in a hurry, come to the left, come on, put it." Zhang Fan is also nervous. The assistant in the system can do whatever you say, but not in reality.
"Eye forceps fixed, fast." It was well positioned and completely covered the wounded's face. Look down from the shadowless light at this time. Just like a faceless man, his eyes, nose and lips are all covered.
Fixed, Zhang Fan moves faster and faster. After the piglet skin is separated from the physiological fluid, if the circulatory system cannot be quickly connected, this thing will die.
Start the operation under the microscope and establish the channel first. Allogeneic transplantation can not damage the inner layer of human blood vessels, because various signal factors will be exposed after injury. Once the human body is exposed, it will become a battlefield.
Under the microscope, the hemostatic forceps are opposite to the hemostatic forceps, pinch the blood vessels of the human body and pull off the external mold of the blood vessels. Human blood vessels can be divided into three layers. A large number of factors are stationed in the inner membrane, the middle layer is the muscle layer, and the outer layer.
The inner layer is the most sensitive, the middle layer is the slowest, and the outer layer becomes sensitive. The inner layer cannot be destroyed. Once destroyed, it can release various factors and transfer various generals. The outer layer can be destroyed and pull off the outer layer of the interface.
Then insert the blood vessel head without outer skin into the blood vessel of piglet skin. The muscle layer of human blood vessel is pasted on the inner layer of piglet blood vessel. The muscle layer doesn't matter. As long as you have clothes to wear.
Then there is the suture. The difficulty comes. At this time, the suture should not only penetrate the blood vessels of the piglet and the blood vessel muscle layer of the human body, but also the inner layer. It is really a Taoist temple in the snail shell. Who dares to do it without hundreds of exercises and muscle memory? Who can?.
One stitch at a time, move forward a little bit. Zhang Fan's slow breathing and countless exercises in the system have already enabled him to produce a feeling of breaking through blood vessels. This is in exchange for countless hypoglycemic symptoms, and all kinds of mysterious dizziness.
Even Professor Li Housen and Professor Yan Dehua, who were on the sidelines of the operation, did not dare to speak out.
Although they couldn't see the specific operation, looking at Zhang Fan's super stable hands, Professor Li Housen's face turned red and kept shouting: "that's it, that's it."
"Too stable!" The experts in the conference room looked more and more poisonous. When they began to sew, they saw it.
"Yes, it's too stable. I just don't know how long it can last. The operation doesn't take an hour or two. Ah ~! "
At this time, the blood vessels are like two intersecting rubber tubes, one covering the other. First suture the front, and then turn over 180 degrees to suture the other side.
Zhang Fan lifted the vascular adventitia. If the fracture is calculated according to this clock face, it should be stitched at 12 o'clock first, and then stitched at the opposite 6 o'clock.
Sew the third stitch at 2 o'clock, the fourth stitch at 4 o'clock, turn over, the fifth stitch at 8 o'clock and the last stitch at 10 o'clock. Each suture has to pass through the blood vessel twice. It's really difficult. It's just like smoking in a gas station. It may explode with one breath.
Every time you sew, bean sweat comes out. It's really difficult to control the strength and continuous output. The left and right hands should cooperate very skillfully. It's as brittle as the inner membrane of a raw egg. After sewing once, Zhang Fan had to stop and wipe his sweat once to restore the energy of his muscles a little.
"Glucose!" Zhang Fan felt a little dizzy. It took more than three hours for the skin on his face to reach the lower jaw. Greedily drank a mouthful of high concentration glucose and continued.
Small blood vessels, small nerves, micro lymphatic vessels, one more difficult to deal with, one more complex. If the blood vessels are not sutured, the skin is inactive, the nerves are not sutured for a little longer, the skin shrinks, the lymph nodes are not sutured, and the later stage is endless swelling.
What else can I do? Liver. Everyone inside and outside the operating room was worried. The more hopeful, the more worried. The better Zhang Fan performs, the more worried everyone is.
Repair and reconstruct the orbit, stick the nasal cavity along the texture, and repair the lips step by step. Slowly, the original bloody face became acceptable.
"Open the hemostatic forceps!" In an instant, the blood entered the allogeneic skin through the repaired pipe, and the originally pale pig skin became bloody.
"How's it going?" Professor Li Housen asked quietly with a dry voice, clutching his heart together. It's so uncomfortable.
"It should be." Zhang Fan looked at his masterpiece and said slowly, although he can't see a bright smile and rich expression in the future. However, he can walk in the sun and face the world happily.