Chapter 349

Ho ho, the table moved to the ring magnet, Gu Jun did not move, relaxed his mind, did not want anything, let the equipment take his contrast state first.

While the fMRI machine was running, it was located in front of the operating table in the front room. Professor Ma, Dr. Shen and others were looking at the images on several computer screens.

At this point, Gu Jun's brain blood flow is displayed in the image, but only professionals can understand what the signal meaning of different colors and color brightness of different brain regions are, as well as the information revealed by parameters such as Mr value, te value and T2 value.

Let alone Wu Shiyu, Cai Zixuan can only look at the picture and sigh.

"Ah Jun's state is normal." Dr. Shen spoke to them.

After a while, after inputting enough contrast state image data, Professor Ma said to Gu Jun through the loudspeaker in the examination room: "ah Jun, next do the stimulation task, from light to heavy. First of all, I'm going to talk about unusual things. Listen carefully. If you have a headache, don't bear it. Let us know the severity of your situation by shouting. If you can't stand it, please ask me to stop immediately

"Good." Gu Jun in the examination room answered, "Professor Ma, you start."

Professor Ma, with a calm middle-aged face, began to name one name after another: "mantra, deep diver, heterobanyan disease, human body different banyan tree..."

With Professor Ma's voice, the color brightness of brain images on the screen suddenly increased, and Gu Jun's brain neuron activity became more active.

"Different scale disease, ceremony, Dagon, Tian Yiqing..." The more Professor Ma said, the brighter the image color, and the more nervous the people were.

"Ah Gu Jun suddenly issued a pain cry, he felt the brain from dull pain into bursts of sharp pain, has let his body began to a little stiff.

This is his stress state, which is also the task state of this examination. By subtracting the rheogram of the task state from that of the control state, it is possible for the computer to find the brain regions related to the specific psychological operations in the task state. Now, the real-time comparison results are displayed on a screen.

Naturally, Dr. Shen understood the image. He frowned at the moment and whispered to Wu Shiyu: "the blood flow in the prefrontal lobe, amygdala and hippocampus has increased significantly."

Cai Zixuan can't help but sigh. He grabs his bald forehead. These three places are not good

He has read some research literature on PTSD. One of the main research results of PTSD brain imaging is that there are functional abnormalities in the hippocampus, parahippocampal gyrus, amygdala and prefrontal lobe. Therefore, he has the pathological hypothesis of "prefrontal amygdala hippocampal loop".

That is, the damage of prefrontal lobe leads to the weakening of function, which weakens the regulation and control function of amygdala, which makes amygdaloid nucleus excessively enhance the terrorist reaction. The damage of hippocampus itself and the imbalance of connection with prefrontal lobe and amygdala also participate in the damage process of memory of patients.

The blood flow measurement results of Hao Jun are in accordance with the hypothesis of local brain activity.

The location of the brain hemorrhage before Haojun was the right prefrontal lobe. If the injury and related surgery led to the dysfunction of the prefrontal lobe, the cause was found.

"Ah Jun, now increase the stimulation, you think about what happened on that island." Professor Ma added, "once you can't stand it, stop. Don't force it."

Gu junzun fulfilled the stimulating task. His head hurt so much that he could hardly bear it. His breath became gasping.

Next came the most important task. The nurse next to the fMRI machine gave him a document, all of which were pictures of abnormal things such as the corpse of a deep diver and a patient with banyan disease. Gu Jun only saw two or three, the head on the sharp pain appeared before the seizure of the whole body muscle involuntary twitch signs, he immediately closed his eyes and stopped.

The stimulation task of this examination is over, but Gu Jun does not leave the table for the time being, and the machine continues to record the changes of brain blood flow during his recovery.

On the other side, Professor Ma and Dr. Shen looked at the contrast images in the computer, and their faces became more and more ugly, and they were a little surprised

When Gu Jun recalled the traumatic scene, the blood flow continued to increase; when he looked at the stress pictures, he had a dramatic change in hemodynamics, not only in the three brain regions of prefrontal lobe, amygdala and hippocampus, but also in the whole brain. This physiological reaction was much stronger than that of ordinary PTSD patients under stress.

And such rapid whole brain congestion is very dangerous, can lead to sudden increase in blood pressure, it is easy to make the brain microvascular rupture and cause bleeding.

Given Gu Jun's history of cerebral hemorrhage and craniotomy, this level of stress is fatal to him.

"Not optimistic, really not optimistic..." Dr. Shen murmured, not a pessimist, but he felt helpless.

After Gu Jun came out of the examination room, as soon as he saw their expression, he knew that the situation was not optimistic.

When he looked at the results of those images, he was a little confused. Did he have any abnormal function caused by frontal lobe injury? It was very difficult to treat

"Xianjun." Wu Shiyu patted him on the shoulder. "You were still in a coma half a month ago. You'll get better slowly.""Well." Gu Jun nodded to her, and then said to Professor Ma, "Professor Ma, I want to do the MRI and Mrs, check it out."

MRI is nuclear magnetic resonance, which belongs to brain morphometry in brain function examination, while Mrs belongs to in vivo magnetic resonance spectroscopy measurement, which can measure the volume of hippocampus and evaluate whether there is loss or damage of hippocampal neurons. Because the change of hippocampal formation is a typical symptom of PTSD patients.

Do these two kinds of examination need to hit radioactive active substance first, namely contrast medium, before because of worry to cause side use to his body, not easy to use.

At present, both Gu Jun's request and BOLD-fMRI were unable to show the structure of his hippocampus. After a discussion with Dr. Shen, Professor Ma agreed to carry out an examination, but first let Gu Jun rest in the laboratory for three hours. Then the nurse gave him a contrast agent, and then he completed MRI and Mrs.

MRI is an anatomical image, while MRS is a comprehensive recording of all chemical signals in the tested individual. The measurement result is a spectrum of multiple spectral lines.

Gu Jun's MRI images showed indirect signs of hippocampal volume reduction - enlargement of temporal horn of lateral ventricle and disappearance of superficial sulcus of hippocampal head.

Mrs results also showed that the number of hippocampal neurons decreased.

On this day, Gu Jun also did some other tests, such as blood samples to test the level of BDNF (brain-derived neurotrophic factor). The level of BDNF in PTSD patients is usually lower than that in normal people. Now his BDNF level is low, which is much lower than the results of his last physical examination.

The data from the National Bureau of natural science and technology show that the BDNF level of high spirited people is higher than that of normal people, which may also be the source of their awareness.

Now Gu Jun seems not only to lose his high gnosis, but also to have the neuroendocrine characteristics of PTSD pathology.

All these results are put together, Professor Ma, and they all know what the answer is Gu Jun's brain shape did change.

"Ah Jun, you go back to have a good rest and relax. Don't think so much. We will discuss a treatment plan that is most suitable for you." Dr. Shen, pretending to be relieved, sent Gu Jun out of the laboratory.

Then, Dr. Shen and Professor Ma went to the nearby conference room for a remote conference. Tong ye, Yao Shinian, and the director general were waiting for the inspection report.

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