Chapter 722

"Let's sort out the existing data first." Guo Xiang said.

"I have data here." Li Yuanhang handed a floppy disk.

Guo Xiang turns on a computer brought back by Li Yuanhang and prepares to use it.

This computer uses Windows 3.0 system, which is much easier to use than the domestic DOS system.

Moreover, the computer is all in English. It is relatively difficult to operate, but it is also safer. It will not be easy to be used by others.

Domestic computers will be reserved for others in the future, and some students may be recruited at that time.

Insert the floppy disk into the floppy disk slot to read data.

The data are complete, mainly the virus data and current drugs studied by Dr. Hua.

"Can I use this?" Guo Xiang is a little worried.

"Yes, with the permission of Mr. Hua, and many drugs are available on the market and used in clinic. They can be collected if you want to collect them." Li Yuanhang said.

"That's good!" Guo Xiang copied the data on his computer.

There are four main categories of drugs.

Nucleoside reverse transcriptase inhibitor (NRTI): the molecular structure of this drug is similar to that of natural deoxynucleotides. It can be added to the DNA chain instead of deoxynucleotides to terminate DNA synthesis. Zidovudine, lamivudine, tenofovir and ntriptabine all belong to this class of drugs.

Non nucleoside reverse transcriptase inhibitor (NNRTI): the molecular structure of this drug is completely different from that of nucleoside. It is combined with other parts of reverse transcriptase, making the reverse transcription process impossible. Nevirapine and efavirin belong to this class of drugs.

Protease inhibitor (PI): combined with protease to inhibit protease activity.

Integrase inhibitor (insi): combined with integrase to inhibit integrase activity.

"Now we mainly use three kinds of antiretroviral drugs to treat AIDS, like cocktails mixing different wines, we call it cocktail therapy." Guo Xiang said.

"Cocktail therapy? It's a little interesting! " Li Yuanhang nodded, "you are very creative."

Guo Xiang smiled guilty. In fact, this was put forward by Dr. Hua Hongmin in his previous life. He just borrowed it in advance, but how to dispense the medicine still needs a lot of experiments.

At that time, if you can really succeed, write Dr. Hua's name in front of you. You don't dare to monopolize the credit.

"These three drugs are not randomly matched. They must contain two nucleoside reverse transcriptase inhibitors and one other type of drug. In this way, the problem of drug resistance of single drug can be overcome. " Guo Xiang continued.

"You're right." Li Yuanhang nodded, "now we have more than a dozen drugs here. Which two nucleoside drugs are matched with the other, and how much the ratio is, we have to go through many experiments to know. It's not just a few times. "

"That's natural. It's not that easy." Guo Xiang nodded and made an approximate drug type ratio on the computer.

Li Yuanhang was very curious when he saw her make a chart. In the chart, all types of drugs are matched with other drugs respectively. At that time, just experiment one by one according to this.

"What is this?" Li Yuanhang was surprised. This watch is well done.

"This is a mind map." Guo Xiang Xiaoxiao, this is widely used in later generations, and she often uses it. It can be used in all fields and is easy to use.

"At a glance, clear, very good." Li Yuanhang praised.

"Thank you." Guo Xiang smiled, "if you want to learn, I can teach you."

"Really? That's great! " Li Yuanhang couldn't wait to sit next to Guo Xiang. He thought he had a lot to teach Guo Xiang when he came back from studying abroad. Unexpectedly, he had to learn from her first.

And she knew far more than he thought. He thought it was incredible. Where did she learn it?

"You see, there are many types of mind maps that you can use as needed. There are tree, fishbone, map distribution, bubble chart, flow chart, bridge chart, etc. for example, we can use experiments, lesson preparation, process flow, etc. "

Guo Xiang's men kept explaining to Li Yuanhang. Li Yuanhang was very surprised and listened with interest. With this mind map, it would be much easier to do some analysis.

Guo Xiang talked for a long time. Li Yuanhang listened carefully and began to do it himself.

At this time, there was a knock on the door. They looked up and saw that headmaster Lin was coming. They all stood up, "headmaster Lin!"

"Busy?" Headmaster Lin smiled and nodded and looked at Li Yuanhang. "Miss Li, what do you think of our laboratory?"

Now Li Yuanhang is a member of Beijing Medical University. Naturally, he can also be called a teacher. Although he only graduated from a master's degree, he is a world-famous school and his status is a little different.

"Good, unexpected." Li Yuanhang said with a smile.

"Yes, I was shocked when I came to see it the other day. It's very different from before. Look here. It's not too much to say that modernization has been achieved." Principal Lin smiled.

"Today, I installed the biological experiment cabinet and computer. Headmaster Lin, will you see if you have made further progress?" Guo Xiang smiled.

Principal Lin was surprised, "so you all use computers here? It's so advanced. "

"Why are there four?" Mr. Lin asked.

"I bought two, and Li Yuanhang brought two back from the United States, so there are so many. However, headmaster Lin, you can rest assured that it will not be wasted. It will certainly be used in the future. Our laboratory must recruit students. We can't do experiments alone. " Guo Xiang smiled.

"That's true. Miss Li, you should teach Xiao Guo more. " Headmaster Lin said.

"Headmaster Lin, you are joking. Miss Guo is more skilled than me. She taught me just now. Look at this picture. She taught me to do it." Li Yuanhang said modestly and had to admire him. He was really powerful.

"Really?" President Lin was surprised that the things on Guo Xiang's computer were indeed more complex than those in Li Yuanhang's computer. Was this student even more powerful than those who came back from studying abroad?

However, it's not surprising to think that her family has so much money and may have used the computer long ago.

Anyway, he doesn't understand this. I think it should be like this.

"Is there any difficulty?" Mr. Lin asked.

"We also need small animals for experiments, mice and rabbits." Guo Xiang said.

Later experiments should implant the virus into animals and then use drugs to see the effect.

"Yes, these are essential." Li Yuanhang also nodded.

"This is no problem. The school also has other laboratories and special feeding experimental animals. Just go there and catch them at that time." Principal Lin replied.

"That's great." They answered.

In this way, you can start the experiment now. First catch a few white mice and implant the HIV virus first. When you get AIDS, you can start the drug test.

(PS: all relevant drugs are based on relevant knowledge on the Internet.)