Chapter 157

Hearing Zhou Wen's words, Zhu Linqing secretly said "bad.".

Listening to the other party's meaning, it is clear that cro enterprises have offered more favorable conditions.

After hanging up the phone, Zhu Linqing looked at the computer on the new version of sildenafil granule patent technical specification, and could not help frowning.

Although Yaoming Kant's conditions are harsh, they are "conscience price" in the industry. The general cro enterprises dare not say that they can be better than the conditions given by Yaoming Kant.

Since the cro enterprise dares to rush for food, it must also see the huge market potential of this drug.

Even, sildenafil granules have been made in advance according to the technological process, and preliminary clinical trials have been conducted. The efficacy is very significant, so we can't wait to cooperate with Zhou Wen.

After some analysis, Zhu Linqing thinks his guess should be close to the truth.

Thinking of this, he immediately picked up the phone and called the lab.

"Hello, director Shao, I sent a document to your email. You should make it for me as soon as possible according to the above technical process. Within 48 hours, I need to get the efficacy evaluation report."

Two days later

Zhu Linqing got the efficacy test report.

Skim over the previous toxicology test data reports and directly see the results.

Number of participants: 6.

There were 2 mild ed, 2 moderate ed and 2 severe ed.

According to the test results, the new sildenafil granule has a particularly significant effect on the treatment of ED symptoms. All 6 participants have very good data

Zhu Linqing looked at the test report, his intestines all Regret Qing.

If the side effects are not too obvious in clinical trials, it is almost 100% to replace the old sildenafil tablets after coming into the market.

"No, I can't just give up..."

Zhu Linqing immediately decided to have a detailed interview with Zhou Wen.

No matter how bad it is, we have to find the company that intercepts the Hu and take a share of the share.

……

On the other side, Xu Yuting came to Jiangzhou on the afternoon of the 30th.

At 3 p.m. on December 31, I met Zhou Wen in the office of Hengfeng building in Jinhu district.

In addition, Chen Zhiyuan and lawyers from both sides were also present.

"Hello, Mr. Xu"

"ha ha, hello ~"

when two people shake hands, they also look at each other closely.

In Zhou Wen's eyes, Xu Shuangyu is an excellent and elegant girl. She is different from the so-called strong woman. Xu Yuting is full of the personal charm of a female entrepreneur, which makes people feel good about her.

In Xu Yuting's opinion, Zhou Wen looks more real than that brilliant young genius on the stage.

"This is Chen Zhiyuan, general manager of Huanyu."

"Hello, Mr. Chen."

"Hello, Mr. Xu. Please have a seat."

"Well, ok..."

Xu Yuting is a standard businessman, and Zhou Wen is also considering how to maximize the benefits of patents.

So there is no too much politeness, after a few simple greetings, it is straight to the theme.

In fact, Xu Shuangyu has said the conditions of Longkang.

Zhou Wen authorized the new sildenafil granules to Longkang, which was responsible for the promotion and operation.

The money we earned was 19 cents.

Long Kang 90%, Zhou Wen 10%.

Don't get excited.

Zhou Wen's 10% is 10% of the total sales.

Remember, it's sales.

In other words, if the new version of sildenafil granules is listed, the annual sales volume will reach 1 billion, and Zhou Wen will get 100 million yuan.

10 billion is a billion.

Although Longkang group took 90% of the total, they were responsible for clinical trials, new drug marketing and marketing.

Secondly, the profits of the downstream dealers are divided into these and deducted from the 90% of the profits. In fact, the profits of Longkang should be greatly diluted.

In addition, the two sides have a minimum agreement.

After the signing of the agreement, whether sildenafil particles can be listed or not and how the sales are after the listing, Zhou Wen must be paid a patent fee of 20 million yuan per year (included in the sales volume).

Because of this, after taking all costs into account, Longkang basically did not make money in the first three years. If you don't make money, you lose money.

So Longkang gambles in the late market.

Won the club model, lost the sea work.

Xu Yuting and Zhou Wen discussed some details of the contract, but the overall direction remained unchanged.

After studying and discussing for half an hour, Chen Zhiyuan, on behalf of Zhou Wen, formally signed an authorization contract with Longkang.

Zhou Wen's authorized subject is not himself, but Huanyu Biotechnology Co., Ltd.

Because he is a technology shareholder, he has given the patent right to Huanyu Biotechnology Co., Ltd., and then authorized by Huanyu to Longkang group.When the shares are discussed again, the patent right will be changed to the main body of the company.

This can not only improve the intangible assets and corporate image of enterprises, but also involve the application for government projects, patent subsidies, and reasonable tax avoidance

In short, there are many advantages.

"Mr. Xu, happy cooperation."

"Happy cooperation ~ after the new year's day, the 20 million guaranteed royalty will be paid to the account of Huanyu first."

"Well, ok..."

Then Zhou Wen sent Xu Yuting downstairs.

Arriving at the door of the company building, Xu Yuting suddenly said with a smile: "by the way, Pisces will return home next week."

At the same time, Xu Yuting looks at Zhou Wen's expression.

Zhou Wen said with a smile, "well, she told me to invite her to dinner when she comes back."

Xu Yuting didn't see anything on Zhou Wen's face and said with a bright smile, "I'll go first."

"OK, Mr. Xu, take your time..."

Zhou Wen watched Xu Yuting's spenter start slowly and disappear in sight.

He turned and went upstairs, took some things and was ready to leave.

Chen Zhiyuan came over and said with a smile: "Hey, Lao Zhou, the last time that Xiaomin, has been asking me why you can't get through to your phone, you pulled her black?"

Zhou Wen said, "no, I just casually reported a number."

Chen Zhiyuan bared his teeth and said: "niuforced, you have preliminarily mastered the essence of not taking the initiative, not refusing and not being responsible."

"Get out of here, because of you, I'm all degenerate now."

"Don't say that. Everyone has a love for beauty. At most, it is a little fraternity. How can it be called depravity? "

"OK, OK, go on with fraternity. I went to the laboratory ~ "

Zhou Wen took the car key and was ready to leave.

"Lend me your car. I'll see a client later. My car is too much," Chen said

"Then give me your car." Then Zhou Wen threw the key to Chen Zhiyuan.

"I lent my car to people in the company to do business," Chen said

Zhou Wen had no language: "what am I driving?"

He said, "Ferrari, you laugh. Tens of millions of cars can't be thrown into the garage every day. "

Zhou Wen: "so Sao Bao, how can I drive to the laboratory?"

"Or Can I borrow an electric car for you from Xiao Liu at the front desk

"Roll ~"

"Ai ~ OK." Chen Zhiyuan ran away with the key.

"That's the Sao Bao." Zhou Wen is too lazy to call didi car. He takes the key of Ferrari f12tdf from his office and goes downstairs.

……

World Biotechnology Institute, 404 Jinhu Industrial Park.

In the open office, seven or eight people, including Wang Hua, Sun Xin, song Xuezhang, Bai Xuan and Luo Chunlei, are gathering to study and discuss.

This is the person in charge selected by many doctors themselves. He has excellent academic character and certain leadership ability.

We all agree.

The technology they are discussing at this time is "mutation breeding", which is one of the key projects to be developed in the next step.

The so-called mutation breeding technology is similar to the rice aphid gene transformation technology studied by Zhou Wen before.

It is to use physical, chemical and other factors to induce the mutation of organisms under artificial conditions, and then select and cultivate new varieties of animals, plants and microorganisms.

For example, chemical mutagens are more commonly used alkylating agents, such as ethyl methanesulfonate (EMS) and diethyl sulfate (DMS).

The method is very simple, dilute it to a certain concentration, and then put the seeds to be mutated and soak for a period of time.

After that, the seeds germinated, and the plants with the required phenotype were selected, and then the mutants that could be stably inherited were selected by self crossing or hybridization.

Of course, the workload of screening is very large, for example, sometimes it is necessary to screen tens of thousands of seeds to find the desired traits.

There are also physical mutagenesis.

Its principle is to use a variety of radiation to accelerate the mutation rate of plants, among which gamma ray, α - ray, β - ray, gamma ray, Χ - ray, ultraviolet radiation and so on are commonly used. These operations need special equipment.

One of the more famous is the laboratory of Japan benzene Radiation Breeding Institute. They built a tower for radiation treatment, surrounded by a field.

After some discussion, we selected two research objectives - grapes and strawberries.

These are two kinds of fruits common in greenhouses in eastern Jiangsu Province.

Just as they were ready to assign tasks, the sound of footsteps came from the door of the conference room. People turned their heads subconsciously and found that it was Zhou Wen who had come.

"Zhou Suo is here."

"Zhou Suo Hao.""Ha ha, everyone is here. Sit down..."

Zhou Wen reached out and motioned for them to sit down. Then he sat down beside Wang Hua, "what are you talking about?"

At the same time, he has seen the research schedule on the table, as well as the relevant materials about mutation technology.

Song Xuezhang, sitting opposite Zhou Wen, said, "we have just chosen two targets..."

With song Xuezhang's account, Zhou Wen's ears suddenly sounded four or five task prompts.

Zhou Wen:

He has never received so many tasks at once.

Open the system tasks and have a look. There is a long row of new tasks on the list.

[task 1: radiation breeding.

Requirements: establish a research group of grape radiation breeding.

Reward: 2000 discipline experience, 1000 points, one prize opportunity (bronze)]

[task 2: chemical breeding.

Requirements: establish grape chemical breeding research group.

Award: 2000 discipline experience, 1000 points, one prize opportunity (bronze)]

[task 3: radiation breeding 2.

requirements: establish strawberry Radiation Breeding Institute 】

the requirements of task 3 and task 4 were almost the same, except that the requirements changed from grape to strawberry.

The first few tasks, in his view, are the system to send points.

But the latter one is exaggerated.

For example, task 5 requires the cultivation of grapes with an average of 50 grams per grain.

Fujimino grape, the largest grape variety in China, has an average of only 22-30 grams per grain, and the largest grape variety is only 35 grams, which has nearly doubled.

Task 6, it is required to cultivate a single strawberry with a maximum of 500g.

This is even more exaggerated. The world record is only 231g, which has more than doubled. The system really looks up to him

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PS: sorry, please

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