Chapter 2098

Acetaminophen was called paracetamol a long time ago. As the name suggests, it can relieve fever and pain.

By inhibiting prostaglandin synthase in hypothalamic thermoregulation center, the drug reduces the synthesis and release of prostaglandin PGE1, resulting in peripheral vasodilation and sweating. Its antipyretic effect intensity is similar to that of aspirin.

The analgesic effect is not strong, only for mild to moderate pain.

N-acetylcysteine, a sulfhydryl donor, is a specific drug for acetaminophen poisoning.

Zheng Ren saw this in the doctor's order and knew that ICU had used symptomatic drugs, so he didn't say nonsense.

The severe force of 912 is quite powerful. Except for the strange situation of inexplicable discoloration of urine caused by propofol, Zheng Ren doesn't think he needs to talk too much.

In the face of a patient with liver failure caused by acetaminophen poisoning, collective strength is needed.

This is a definite diagnosis. An experienced old doctor can know what the disease is at a glance.

But the treatment is very difficult, even more difficult.

"Why did you eat so much Yinqiao Tablets?" Su Yun looked at the medical record and frowned, "I really think Yinqiao Tablets are traditional Chinese medicine?"

Professor Zheng Renhe and Professor Yang sighed, and no one said anything.

The description of Yinqiao tablet says - expelling wind, relieving exterior, clearing heat and detoxifying. It is used for fever, headache, cough, dry mouth and sore throat caused by wind heat and cold.

The standard vocabulary of traditional Chinese medicine gives people the feeling that it is traditional Chinese medicine.

In case of a cold, many people are willing to add a group of Yinqiao Tablets orally, and the effect is really good.

However, we should carefully read the instructions of Yinqiao tablet, but its composition is not so simple.

Honeysuckle, Forsythia suspensa, Schizonepeta tenuifolia, light Douchi, light bamboo leaf, burdock, reed root, Platycodon grandiflorum, licorice, chlorphenamine maleate, paracetamol, vitamin C, peppermint vegetable oil.

Chlorphenamine maleate, also known as chlorphenamine, is an antihistamine.

This drug component plays an anti allergic role by antagonizing H1 receptor. It is mainly used for rhinitis, skin and mucous membrane allergy and relieving cold symptoms such as tears, sneezing and runny nose.

Next, it also contains acetaminophen, a small amount of which will reduce symptoms, and a large amount of which will lead to liver failure.

Each Yinqiao tablet contains more than 100mg of acetaminophen.

So its effect is good. It goes back to acetaminophen.

In addition, other cold medicines also contain acetaminophen. The child named Chen Li not only takes it twice, but also uses several drugs in combination.

Acetaminophen intake... Is almost lethal.

Each kind of medicine has its effect and benefits the human body. At the same time, it will also have hidden dangers.

Take a lot, not to mention drugs, even bananas. Don't eat bananas, even if you drink too much water.

The word "appropriate" is right.

Zheng Ren looked at the medical record and his eyebrows were about to be tied together, like the belt of sterile surgical clothes.

The child named Chen Li is difficult to save. Zheng Ren makes a judgment in his heart.

In the process of looking at the medical records, the directors and professors of relevant departments in the hospital came one after another.

Vice President yuan presided over the hospital consultation, and director ye and deputy director Lin of the medical department all attended.

At the sight of the importance attached by the hospital, everyone's heart sank again.

Unlike diseases such as cancer, if a cancer patient is ill, life and death are inevitable. Just try your best.

In front of me is a young college student. He has studied hard for more than ten years in a cold window. Before entering the society, the good one is about to die.

This alone, Zheng Ren felt that the patient's family could not bear it.

White haired people send black haired people, which is the great sorrow in the world. The world of mortals is more miserable than this.

The ICU reports the medical history to the inpatient general manager. Try to report the known medical history as concisely as possible. The doctors who come later have a basic concept of this.

Acetaminophen poisoning, acute liver failure, peritoneal effusion, coagulation dysfunction and so on.

ICU has begun to supplement platelets and treat patients with artificial liver blood purification technology.

Artificial liver blood purification technology refers to plasma exchange and blood adsorption technology.

The inflammatory substances or toxins dissolved in the blood are adsorbed to solid substances with rich surface area, so as to remove inflammatory substances and poisons from the blood.

For the student named Chen Li, it is mainly to filter out the residual acetaminophen in the liver and blood.

Artificial liver technology is specially used for blood detoxification.

It uses the method of "blood exchange" to discharge the toxin from the patient's plasma, that is, to replace the patient's plasma containing toxin with healthy plasma, and about 50% of the whole body's plasma is replaced each time.

But this is a measure to make up for the lost, so as not to let the residual acetaminophen in plasma continue to damage the liver.

However, the damaged liver can not be treated by artificial liver blood purification technology.

In 1986, Professor Li Lanjuan of the First Affiliated Hospital of Zhejiang University and her team carried out the research and clinical application of this technology.

Up to now, it has been a relatively formed technology. The 912 critical care doctors have mastered it skillfully and have no problem in application.

After reporting the medical history, there are many speeches by directors and professors.

In fact, there is not much to say.

Disease, that's it.

This is the case.

The patient had a rapid onset. Although he was sent to the hospital in time and responded appropriately, his condition was not optimistic.

This can be seen clearly on the faces of the chief inpatient, second-line professor and director of ICU.

They have a judgment on the patient's condition and hope that the patient can get better quickly after symptomatic treatment.

Only during the period from taking over to treatment, they have their own judgment.

Rich clinical experience silently says that now all treatment methods are available, but the probability of patients' recovery is not large.

Not to mention the expensive treatment cost, the daily cost of this patient is at least more than 50000. Just the severity of the disease

Thinking of this, Zheng Ren has a headache.

"I suggest preparing with both hands and matching organ transplantation. If conservative treatment is ineffective, liver transplantation can be performed." Professor Yang spoke. What he said was very simple.

"Where's Dr. Zheng?" Vice President yuan looked at Zheng Ren and asked seriously.

"I agree with Professor Yang. I haven't seen the patient yet, but according to the drug dose calculation in the medical record, the patient takes too much acetaminophen. I don't think it is possible to improve and correct liver failure through various first aid measures."

"I suggest preparing for liver transplantation... If we can find the source of liver."

Zheng Ren said firmly.

Liver transplantation, in Zheng Ren's view, only liver transplantation can save the child.