"Yes, I remember that major depressive disorder is a very serious mental disease. It is said that it comes from the combination of genetic and environmental factors, and stress is the main environmental risk factor." Ringer is also skeptical. He doesn't believe in Dr. Lancer Penn's views and treatment.

"There are still principles." Although Zheng Ren doesn't believe that fecal transplantation can treat severe depression, he still tells the truth, "more and more evidence shows that microbiota is an environmental factor, which can shape the brain through microbiota gut brain axis, and mice with changed microbiota usually show depression related behavior."

"It is said to be related to the NLRP3 gene." Su Yun added.

"What n?" Ringer was stunned.

"Er..." Zheng Ren found it difficult to explain clearly. He thought for a moment and said, "in short, it is to make the feces of mice knocked out NLRP3... A gene related to depression into capsules for patients to take orally."

“……”

Linge and director Kong were stunned.

Although I have experienced many battles, I feel disgusted when I think of Huanglong soup and mouse feces. Now we have to take orally the feces of mice. Can this really cure the disease?

"Director Lin, what's your expression?" Su Yun was so happy that he pretended to be very serious and looked at linge, "eat mouse shit, which has been there since ancient times."

"I do know that there is a snack for children called mouse excrement. Friends in Jinling are still looking for it all over the world during the new year's festival. Unfortunately, it's selling less and less."

"The one you're talking about is a snack made of tangerine peel, plum, white granulated sugar and hawthorn." Su Yun said with a smile: "in a word, you'll expose your age. Who still eats rat shit?"

"Memories, memories."

"There is mouse excrement in traditional Chinese medicine, do you know?" Su Yun pulled the topic back like a prank.

"Wulingzhi, the feces of compound tooth flying squirrels." Zheng Ren said, "it mainly cures the cold air in the heart, five infantile chancre, dispels epidemic diseases, cures intestinal wind, dredges Qi vessels, and closes the moon for women."

"It's unprofessional of you to say so..."

"Just know the meaning. Why are you so professional?" Zheng Rendao, "the treatment of severe depression by fecal transplantation is still in the stage of animal experiment, and I am not optimistic about this animal experiment."

"Just because we can't judge whether the mice are really depressed? In fact, we can judge it through activities, communication and play." Seeing that Zheng Ren didn't want to say, Su Yun smiled and went on to talk about the treatment of depression.

"If you treat Clostridium difficile infection, you can try fecal transplantation, but the risk is great." Zheng Ren said, "but..."

"Don't be ridiculous. They asked American experts for treatment. Can you believe that you just deny it so carelessly, and the people of Director Mao's family kicked you out directly?" Su Yun breathed, his black hair floating on his forehead.

"Not really."

"What's wrong? I heard that Director Mao is in the stage of onset. No matter who he sees, he grabs his hands and says sorry. He has a very good memory and talks about a little details for a long time." Su yundao.

"Oh? I think my life is worthless, extreme guilt, remorse, helplessness, despair and self abandonment. These points are quite consistent with severe depressive disorder." Zheng Ren said, "if so, there's no good way."

Ringer listened to Zheng Ren and bowed his head and sighed.

"Cut, are you talking about DSM-IV-TR diagnostic criteria or ICD-10 diagnostic criteria?"

"Neither." Zheng Ren didn't want to quarrel with Su Yun at all today. He said directly: "I still agree with director Mei that normal drug treatment. Fecal transplantation, whether oral capsule or intestinal, may induce more and bigger problems."

"OK, boss Zheng, I'll reflect your views to the hospital." Ringer finally said cautiously.

"For fecal transplantation, there have been many new studies recently. For example, in a August 2019 cell research study, the Erick Riquelme and Florencia McAllister studies of the Anderson cancer center in the United States found that a small number of long-term survival patients with pancreatic cancer had significantly more diverse microbes.

"Can fecal transplantation treat cancer?" Ringer was surprised.

"It's just a discovery. It will take a long time to study whether it works or not." Zheng Rendao: "it may also be a wrong direction. Fecal transplantation is a good thing, but I don't think the means in the experimental stage should be used in clinic."

"OK."

Ringer nodded, then stood up and said, "boss Zheng, I'll report to the hospital."

"Director Lin said that after Director Mao and her husband confessed, her husband was so angry that he slammed the door and left. Is there anything wrong?" Su Yun continued to gossip.

Ringer smiled bitterly.

"Why do you ask so many questions? It has nothing to do with diagnosis and treatment." Zheng Rendao.

Hearing Zheng Ren say so, ringer smiled apologetically and turned away.

Zheng Ren then spoke to director Kong and left the office.

"Boss, do you really think fecal transplantation is unreliable?" Su Yun asked.

"It's not unreliable, but after a long time of research. The treatment of Clostridium difficile has been used clinically, but the mortality is very high."

"If not, the mortality rate is nearly 100%." Su Yun went back directly.

"Who knows, the method of medical treatment has nothing to do with us." Zheng Ren doesn't want to think about this. Being a surgeon is enough.

"Boss, intervention discipline, subordinate to imaging specialty, is a clinical auxiliary discipline." Su Yun's mouth owes much, misinterprets his meaning, and directly connects with Zheng Ren's weakness.

Zheng Ren was too lazy to take care of the goods and went back to the office to continue reading.

This time he was looking for information about fecal transplantation.

Fecal transplantation wants to become a routine treatment in clinic, which can't be done in 20 or 30 years.

Zheng Ren just looked fresh and didn't want to study from beginning to end. Even the skill of real eye has cooled down, and Zheng Ren doesn't want to use it.

Who knows the scope behind a study. If you use it casually, you may directly drain your energy and faint.

Zheng Ren loses once and learns once. The real eye can't be used casually. Gastric fundus and left gastric artery embolization can be seen at a glance. After all, is it simple.

As for fecal transplantation

As a new treatment method, it involves too many categories. Treatment of dysbacterias, treatment of depression, treatment of cancer, treatment of diabetes, seems to be able to figure it out.

There are a lot of data. Zheng Renyue is more and more broken. He uses his real eyes to explore the truth. It's so majestic. It's estimated that it won't be fainting, but really dead.