Chapter 120： Cas9 (subscription required)

Chapter 120 Cas9 (seeking subscription)

Su Hao has summarized the regularity of the gene sequence between ordinary Zhu Huo people and foreign people through comparative studies over the past few years.

If all the genes are arranged in order, so that they are under the same chain.

Easily compare the genetic differences between strangers and ordinary people.

Su Hao also found the difference between strangers in this way.

There are more fragments in the genes of foreigners than those of ordinary people, which are long and short, and they are located in different positions.

Make a simple analogy.

Compared the genes of an ordinary person to the sentence "I eat".

This sentence contains three parts of "subject, predicate and object", which is complete and can express clear meaning.

The gene of the other person is to insert some "fixed supplements" in this sentence, and complete it, so that this sentence can express a stronger and more targeted meaning.

Such as "My mother called me to go home for dinner".

This sentence has evolved a little bit compared to the previous one, and it feels stronger. Then if you make this stronger, the order "first-level" represents the genes of the first-level alien.

Continue to add vocabulary to this sentence, it can become "My mother called me to go back to grandma's house for dinner".

The meaning of    expression is more clear. This gene is more abundant. We compare it to "secondary", representing the genes of second-level aliens.

So, when we continue to add appropriate vocabulary to it, this sentence can express a stronger meaning.

Such as "My mother called me to take my girlfriend back to my grandmother's house for dinner".

This sentence is undoubtedly the "third level".

The same applies to the genes observed by Su Hao. The genes of ordinary people are the basis. On this basis, after inserting various specific fragments of gene sequences, another special expression is obtained.

And this way of expression is the special power of strangers.

By comparing the genes before and after Yashan's evolution, Su Hao confirmed this even more.

Su Hao knew that creatures in this world had mastered a method to edit their genes according to certain rules.

is the carving knife in the hands of Anunnaki in the Sumerian mythology.

"So, how did they complete this process of modifying genes?"

Regarding this point, Su Hao also found the answer.

It was precisely because he found this answer that he was trembling with excitement, and even got goose bumps, a kind of spiritual pleasure that filled his whole body and mind.

So what did Su Hao find?

This is the key that he discovered after making extensive comparisons between Zhu Huo's genes and ordinary humans in previous generations.

In fact, it is not complicated.

That is the genes of Zhu Huo people, which are more like bacterial genes, and are fundamentally different from the general large animals.

As for the difference?

To clarify the difference between these, you need to know the genes of bacteria and the genes of ordinary animals.

Everyone knows a common sense.

A normal person, once a virus invades the human body, the white blood cells in the human body will actively identify and clean up these viruses.

Then the question is coming.

There are a large number of bacteria and bacteriophages in the ocean. Since ancient times, the battle between bacteria and phages has never stopped.

However, these bacteria are not used to destroy the white blood cells of bacteriophages, so how do bacteria resist the invasion of bacteriophages?

The answer is simple, it lies in the DNA of bacteria.

Bacteria have two special pieces of DNA.

A section of gene specifically used to record viral gene fragments can be called a database.

A piece of DNA dedicated to the production of weapons can be called a weapon arsenal.

When the phage invades the cell, the weapon depot will produce a kind of scissors. This kind of scissors can be called ‘scissors No. 1’.

'No. 1 Scissors' cut a piece of DNA from the phage, and record the cut DNA into the DNA database.

At this time, the weapon library began mass production of'No. 2 Scissors', and came to the database to retrieve the genetic information of the phage.

Then the No. 2 scissors, which carried the virus information, became the deadly weapon of bacteriophages—Cas9.

Cas9 will actively find the DNA of the phage. Once it finds the matching gene fragment on the phage, it will immediately cut the DNA of the phage.

Complete the kill.

is that simple.

And Su Hao discovered that the Zhu Huo gene of this world is similar to the gene of bacteria.

Because the genetic sequence in Zhu Huo's body also contains a ‘database’ and a ‘weapons library’ on bacterial DNA, not only that, but also an extra switch that looks like a ‘controller’.

In other words, the secret of evolution in this world is actually in those special gene sequences.

Such a discovery, Su Hao opened the door to a new world.

Suddenly discovered that he can really master the method of modifying genes at will.

As long as he can control the synthesis of Cas9.

Can Cas9 be synthesized artificially?

The answer is yes!

Cas9 can indeed be synthesized artificially, but it does not mean that Su Hao can do this, and the basic conditions do not allow it.

But he is not discouraged. It will be a long time in the future, so there must be a way to solve this problem.

Why is Cas9 so important?

This is like the cursor of a computer. We can control the cursor and edit and modify a document arbitrarily. It can be inserted, deleted, or modified, whatever we want.

Conversely, if we can't control the cursor, there will be no way for this document.

Of course, it is also possible to scramble all the documents and then reorganize them, but who can confirm that the articles after the reorganization can be read smoothly?

It is more likely to get a meaningless garbled text.

The same goes for   genes. With the cursor of Cas9, you have the ability to modify genes at will.

"If you want to completely uncover the secrets of evolution, I still need to experience a round of evolution personally, and then collect data." Su Hao is ready for evolution.

And the sequence he chose is the same as the [Shen Jiaren] sequence as Yashan.

Because this sequence allows him to maximize the power of runes.

Although other sequences are very powerful, they are far less compatible with him than [Shen Jiaren].

As for what to do if you want other abilities in the future?

is very simple, as long as his genetic research can make a breakthrough, these are not too big problems.

...

Time flies quickly in Su Hao's research.

One year passed quickly.

Su Hao is ten years old!

Su Hao strolled in this new-looking city, feeling extremely happy.

At this time, the population of Silin City has skyrocketed. Most of them have drifted here from other cities. Once I came to Silin City, I fell in love with this city from the heart.

Without others, ease and harmony.

All this is attributed to the ‘Silin Association’ established by Yashan more than a year ago.

Today's'Silinhui' has developed into a gang of more than two dozen people, and all the internal members are foreigners above the second level.

Dealing with ordinary disputes in the city during the day, and turning into foreigners’ ‘patrols’ at night, catching those strangers who break the rules, beating them violently, and then forcing them to recite the ‘two cores, three principles’.

The current "two cores, three principles" is not as simple as it was a year ago. Many regulations have been added below, adding up to a few hundred words.

All foreigners hate reciting the ‘two cores, three principles’. When they see the ‘Silinhui’, they always walk around.

Can't afford to offend.

After a long time, few people dare to commit crimes again.

Under Su Hao’s suggestion, Yashan also made the rules of Silin City into a slogan. The streets and alleys are all over the city. As long as you open your eyes, you can see the huge fonts.

"Taking the harmonious development of Silin City to build a beautiful city as the core".

"The core is the happiness and happiness of ordinary people in Silin City".

...

Even ordinary people read a lot, and they will memorize those two sentences.

"Boss Wei!"

"Very good boss!"

"Wei boss early!"

Su Hao passed by, and almost everyone greeted Su Hao. In the beginning, strangers would do this, but afterwards, ordinary people did the same, and Su Hao really became the boss of Silin City.

Su Hao smiled and nodded, "Not bad, not bad!"

(End of this chapter)