Chapter 273： The epitome of the times (4)

After breakfast, Zhou Wenhui sent the four little guys to school.

Li Yi and Li Yanshun returned to the living room, the father and son were sitting on the sofa, and the projection TV was broadcasting the program of Star Media.

The host - Xu Qiuxuan 'appeared' in the spaceport and introduced to the audience in front of the screen: "Audiences, we are now located in the space dock below the spaceport, and its inner space is the one hundred and seventy of the Xingyaocheng dock. Twice the size, in the future, it will carry human beings to build interstellar warships, as well as intergalactic spaceships,..."

"Everyone, this is the core of the spaceship dock, the power manufacturing room of the interstellar spacecraft. In the near future, this will be the place where the antimatter power furnace of the spacecraft will be built..."

...

With the 'advance' of the host - Xu Qiuxuan, the sophisticated and magnificent interior landscape of the space dock keeps appearing on the screen, as if you are in a mechanical empire. The interior is assembled by various precision mechanical manipulators and various parts. of.

The extremely sci-fi picture deeply attracted everyone's attention.

"Is this space dock real?" Li Yanshun was stunned and asked Li Yi.

"That's still fake, it's all on the news." Li Yi smiled and replied with a smile.

Hearing this, Li Yanshun nodded with relief, looking at Li Yi as if looking at someone else's child, full of inconceivable.

"It's amazing, Xingyao Technology is getting better and better. You can do such an advanced and huge project. It's amazing!" Li Yanshun looked at Li Yi and praised him sincerely.

Xingyao Technology is an enterprise founded by Li Yi. Over the years, every time it grows, it can create various surprises for the world. Li Yanshun has always watched it. However, as Li Yi slowly retreated into the background, he was busy With his grandson, Li Yanshun has not paid much attention in recent years.

Today, suddenly seeing such a magnificent spaceport building, Li Yanshun realized that Xingyao Technology has grown to a point that he needs to look up to.

Facing his father's praise, Li Yi smiled humbly and explained: "It's all the credit of everyone, as well as the excellent Dahei, the construction of the spaceport is solely responsible for it."

"Oh! It turns out that Da Hei is so powerful!" Li Yanshun looked at Da Hei who was lying in the corner and was harassed by several puppies, and was extremely surprised.

"Da Hei, come here." Li Yi smiled and waved at Da Hei.

"Okay, Master!" Da Hei answered the order and walked towards Li Yi and Li Yanshun.

"The old man knows some company affairs, you can introduce it." Li Yi introduced it with a smile. After speaking, he looked at Li Yanshun and said, "Dad! I still have something to do. I'll go back to the study first."

"Yeah! Go get busy! I'll chat with Da Hei." Li Yanshun nodded and looked at Li Yi.

Da Hei sat obediently in front of Li Yanshun, waiting for the old master's order.

Li Yanshun looked at the back of Li Yi's departure, and was very relieved. No matter what Xingyao Technology will become in the future, and what achievements Li Yi has achieved, he will always be his son. It makes him feel very happy to have such an excellent child. of pride.

Back in the study, after closing the door, Li Yi immediately connected to Professor Wei Hanzhi remotely, concerned about the progress of the genetic enhancement scientific research experiment.

The virtual video was quickly connected.

Professor Wei Hanzhi, as well as Professor Wang Yangping, Professor Lin Manjun, and other experts and professors were also present, and everyone gathered early to discuss the findings during the experiment.

"In the sixth stage of the fusion stem cell cultivation experiment, it was found that the differentiation of pluripotent stem cells is accompanied by the disappearance of lipid droplets, and excessive lipid hydrolysis causes lipidome remodeling, thereby regulating key mitochondrial phospholipids and inner crest structure, and further reducing acetyl-CoA and Histone acetylation eventually promotes the withdrawal of pluripotency, what do you think about this issue?" Professor Wei Hanzhi looked at the crowd and asked.

"Organelles and metabolic remodeling play an important role in stem cell fate determination, not only providing metabolic substrates, but also participating in the regulation of epigenetics and gene expression. Stem cells have unique organelle structures and metabolic patterns, while organelles and metabolism are gradually recognized as It is a key regulator of cell fate. I think it should be the excessive lipid hydrolysis rate that causes the remodeling of the intracellular lipidome, reduces the key phospholipids in mitochondria - cardiolipin and phosphatidylethanolamine, and destroys the mitochondrial inner cristae structure. Thereby reducing fatty acid oxidation and the production of acetyl coenzyme a,..." Wang Yangping emphasized.

"Well, I agree with Professor Wang, it should be that the reduction of acetyl-CoA causes the reduction of histone acetylation h3k27ac on the promoters of pluripotency-related genes, which accelerates the decline of pluripotency-related genes and the withdrawal of pluripotency. …”

"It was confirmed that there is a correlation between lipid droplet homeostasis and mitochondrial remodeling."

...

As soon as Professor Wang Yangping's voice fell, all the experts and professors at the scene expressed their approval of this technical route.

After Li Yi attended the meeting, he silently watched their discussion without interjecting.

"Very good, if there is no problem, then proceed to the next experiment according to this direction. Do you have any other opinions?" Professor Wei Hangzhi nodded and confirmed to them by looking around the audience.

Everyone looked at each other, the scene became silent, and finally no one gnawed.

"Okay, then follow this adjustment direction and continue with the next experiment." Professor Wei Hangzhi arranged for everyone to speak. After speaking, he looked at Li Yi and asked, "Mr. Li, do you have anything to add?"

"No, let them go! Let's chat." Li Yi smiled and waved his hand.

"Okay! Let's end the meeting!" Professor Wei Hanzhi said to everyone.

The professors nodded in unison, and the next moment, their figures became illusory and disappeared from the virtual laboratory one after another.

Seeing everyone leave, Li Yi looked at Professor Wei Hanzhi and asked with a smile, "The gene enhancement project has cost more than 1 trillion yuan so far, and the investment is very large. Now, you have achieved certain research results. If possible, Is it possible to produce some technical results first when it is appropriate?"

"Mr. Li, what do you mean?" Professor Wei Hanzhi was stunned for a moment and asked in confusion.

In Professor Wei Hangzhi's mind, genetic enhancement is a complete project, how can some research results be produced separately?

"Now, your expression of the human genetic code should be very clear, right?" Li Yi looked at Professor Wei Hanzhi and asked with a smile.

"Of course!" Professor Wei Hanzhi nodded confidently.

"For example: genetic medicines for suppressing obesity, genetic medicines for immune cancer cells, genetic medicines for modifying human defects, ... These have nothing to do with genes that adapt to the cosmic environment, but have genetic technologies that are related to the health of all human beings, creating value. At the same time, it brings the technical achievements of the gospel to the public." Li Yi reminded with a smile.

"Understood, I understand! I will let other scientific research groups follow up quickly and accelerate the promotion of these technological achievements." After Li Yi's reminder, Professor Wei Hanzhi suddenly realized, nodded again and again, and responded excitedly.

"Yeah! You pay attention to the arrangement. Compared to adapting to the gene fusion enhancement project, the speed of these genetic technology transformation results should be faster!" Li Yi nodded with a smile and asked with concern.

"Of course, the fusion of adaptive genes is an extremely complex project that requires a lot of time to verify. It involves foreign genes and requires repeated experiments to verify the potential impact of genetic fusion after gene fusion. Multi-generational breeding experiments, It will take a long time." Professor Wei Hanzhi introduced.

After a pause, Professor Wei Hanzhi looked at Li Yi and continued to explain: "As for genetic medicines for weight loss and various genetic immune medicines, there is no need to go through these tedious processes. As long as the clinical tests can be passed, the results of these genetic technologies can be transformed very quickly. "

"That's good. Compared with the fusion of adaptive genes, these genetic immune agents can be used in a wider range. It is necessary to ensure the speed and quality." Li Yi nodded with a smile and reminded.

"Understood!" Professor Wei Hanzhi responded with a smile, already fully understanding Li Yi's intentions.

Fusion adaptive genes are prepared for Xiang Xian to enter the universe. Therefore, this kind of scientific research project represents the frontier of science, and the number of users used is not too large, which is different from other ordinary gene-enhancing drugs.

For example: genetic medicine for weight loss, there are more and more obese people in the world, especially those poor people who eat junk food, as well as middle-aged people who are getting fatter in their middle age. In total, there are more than one billion obese people in the world.

You must know that many diseases are caused by excessive obesity, such as metabolic abnormalities and cardiovascular and cerebrovascular diseases: causing a series of changes in obesity-related metabolic parameters, abnormal glucose tolerance, abnormal lipid metabolism, hypercholesterolemia, hyperglycemia Triesteremia, low-density lipoprotein production, etc., will also occur with increased blood pressure, increased uric acid, increased waist circumference or waist-to-hip ratio, and increased body mass index. In the long run, cardiovascular and cerebrovascular diseases, namely atherosclerotic diseases, may also occur;

Digestive system diseases: Obesity can affect digestive function, causing fat accumulation in the pancreas, leading to pancreatitis, which affects digestive function and causes indigestion and other manifestations;

Kidney disease: It can lead to the occurrence of kidney disease, called obesity-related nephropathy, such as proteinuria, kidney enlargement, etc., and eventually lead to obesity-related end-stage renal disease;

Bone diseases: In addition, obesity can affect the mechanical structure and physical structure of the body, resulting in abnormal stress on the spine, osteoporosis, and abnormal bone metabolism.

...

It will be a huge contribution to the entire human society if we can develop genetic medicines to assist weight loss and completely solve the problem of obesity.

Not to mention, other immune genetic agents that cure cancer cells, and genetic agents that optimize human defects.

Thinking of this, Professor Wei Hanzhi flushed and couldn't help but get excited.

Li Yi didn't notice Professor Wei Hanzhi's face, instead he frowned and thought about other issues.

"Professor Wei, there are differences in the genes between different races, right!" Li Yi looked at Professor Wei Hanzhi and asked.

"Yes, the genomes of different races are the loci where a single nucleotide variation occurs in the genomes of the three races of white, black, and yellow. We have drawn a map of the differences between the genomes of different races." Professor Wei Hanzhi nodded and confirmed .

The next moment, Professor Wei Hanzhi waved his hand, and the three-point genome map group was called up in front of the two of them.

"In the three sets of gene maps, the vast majority of the 1.58 million single-family nucleotide variation DNA sites are common, and at least 99.99% of the base pairs are the same, but there is still a 0.01% difference. The variation of a single base pair in the DNA chain of the nucleotide polymorphism makes the three races have huge differences in height, skin color, and body shape. At the same time, it also determines the susceptibility to certain diseases. ,..." Professor Wei Hanzhi looked at the three sets of genetic maps and introduced them to Li Yi incessantly.

Li Yi nodded and asked deeply: "Does this difference affect the research on adaptive gene enhancement projects and the research results of various immune-enhancing genes?"

"Of course! There must be subtle influences..." Professor Wei Hanzhi said affirmatively.

"Well, the current use is to use yellow people as genetic specimens for research, right?" Li Yi looked at Professor Wei Hanzhi and asked impatiently.

"That's right! Of course, we should think that we are the master. What do you mean, Mr. Li?" Professor Wei Hanzhi nodded affirmatively and looked at Li Yi in confusion.

"So, to eliminate the two negative effects, you need to invest a lot of money in research and development, right?" Li Yi did not answer Professor Wei Hangzhi's words, but continued to ask.

"Yes! If the research results come out, the genetic medicines of the latter two species will definitely continue to be researched and make some fine-tuning Professor Wei Hanzhi has no idea why, so he nodded quickly to confirm.

"Very good, you can go to Xingyao Media later to sit down and publicize your research results, and mention this matter casually." Li Yi smiled and introduced.

"No problem! However, Mr. Li, what is the purpose of this?" Professor Wei Hanzhi looked at Li Yi and asked curiously.

"Professor Wei, during this period of time, the population of some poor countries has not only not decreased, but has increased significantly, and the rate of increase is very fast. I think their governments should introduce some strategies to limit the population. If they are unwilling, these advanced Genetic technology is fine without helping them research." Li Yi explained with a slight smile.

Hearing this, Professor Wei Hanzhi was slightly taken aback, and immediately understood Li Yi's intention.

With the popularization and application of cold nuclear fusion, new agricultural technology and intelligent technology, the grain output of Longguo has expanded several times and dozens of times, which has also led to the surplus of global grain resources and the open supply to the world. The improvement of nanomedical technology, genetic medical technology, and other technologies has reduced the death of many people. As a result, many poor countries rely on the sale of mineral resources and the purchase of food to feed a large number of domestic people.

This has led to many poor countries, where people have uncontrolled births, resulting in a large number of people who cannot receive education and have a large number of low-quality populations.

With Li Yi's influence, if he puts pressure on him, he can definitely influence the direction of international resources and international policies.

"Understood! I'll go there tomorrow." Professor Wei Hanzhi nodded with a smile and agreed to do the job.

Li Yi nodded with a smile, and then exited the virtual conference room.

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