Chapter 1774： : How about... I will try?

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Inside the Chencang New Pharmaceutical Research Institute of Dongyang High-tech Development Zone.

It has been officially in operation for several months, and everyone is working hard to conduct scientific research, hoping to conquer Parkinson's as soon as possible.

After Chen Cang proposed the similarities between Alzheimer's disease and Parkinson's disease, the progress of the entire scientific research work has been greatly improved!

However, scientific research will always give people an illusion!

That is, every breakthrough makes people feel like a historic progress, and they think they can achieve very good results.

But the result is... After every breakthrough, I suddenly found out that the difficulty of this matter has become higher again!

If you want to solve the problem, the factors that need to be considered and learned, and the subjects are still increasing!

Professor Zhang Mu himself is engaged in the research of Alzheimer's disease, so when Chen Cang proposed that asparagine endopeptidase enzymes can modify tau protein to make it more viscous and toxic.

Therefore, drugs that inhibit AEP can often show certain benefits in the treatment of animal models of Alzheimer's disease.

In this way, is there an enzyme that can increase the toxicity of folded alpha-synuclein?

This question is really complicated!

It can even be said to be like finding a needle in a haystack.

No one can find an "enzyme" in complex tissues to show that this thing is to promote the pathological α-synuclein after folding?

This requires complex biological engineering to deal with!

There were intense and anxious discussions in the office.

Taidanis frowned and said: "The progress of the enzyme project is too slow now. I have not received an accurate answer from Professor Considine so far!"

"Every time I talk about cooperation, the other party is looking for various reasons for excuse."

"Hey……"

Hearing that Taidanis was so disappointed, everyone did not know how to comfort.

Considine and Tedanis used to be very good partners.

But since Tedanis came to China, his reputation in a certain circle is like a crooked butt, and everyone has avoided it.

To be honest, most of the time, scientific research is divided into national boundaries.

Even if many people are unwilling to admit it, they will find a variety of reasons to convince themselves and others.

For example, now, Chen Cang is indeed the person with the fastest progress in the field of Parkinson's research, but why are those powerful experts unwilling to join?

Is it because they are stupid and don't understand?

of course not!

It's not that you are great, everyone will join you.

A very realistic problem, scientific research is always like a competitive relationship.

As long as you do not come up with results, no matter how leading you are, you will not be considered successful!

Just like now, experts in the field of enzyme engineering are needed in the institute.

But this top expert is really hard to find.

Several former partners of Taidanis are now willing to come too few!

However, domestic bioengineering itself is in its infancy, and the research on protein enzymes is really stretched.

Even the simplest enzyme separation and purification uses some biofilm separation technologies that were retired from the United States five years ago.

These are basic research!

But these basic studies determine the superstructure.

No scientific research is created in a vacuum.

As the person in charge, Zhang Mu couldn't help sighing.

The development of domestic medicine is really not only the backwardness of pharmaceutical technology, but also because the development of medicine is a comprehensive discipline!

Medicine is not a simple subject, but a highly sophisticated subject.

It involves physics, chemistry, molecular biology... and many other basic subjects!

Even the separation and purification of enzyme engineering in a small direction is extremely difficult at this moment!

For a while, everyone fell silent.

Yang Lan couldn't help but said, "How about we still find an old friend of the Chinese Academy of Sciences?"

Zhang Mu shook his head: "He has the same skills as Yu Shuangyong, so there is no need to look for it, and the effect is not obvious."

When Yu Shuangyong heard this, he blushed.

Although what Zhang Mu said wasn't very face-to-face, but it was the truth!

The fragmentation and separation of a small enzyme to find the key core has become a problem!

At this time, the door opened suddenly sounded.

The people who were thinking about it suddenly froze for a while, they all froze for a while, and were even taken aback. For a while, everyone was a little unhappy!

Who will be here during the meeting?

Everyone turned around and found that Chen Cang turned out to be here!

Everyone was relieved.

Chen Cang saw that the atmosphere was a little depressed and couldn't help but stunned for a moment: "What's the matter... this is?"

"The atmosphere is so depressing?"

Everyone sighed when they heard the sound.

And Zhang Mu said directly: "Professor Chen, I'm just about to find you and sit down and say."

Chen Cang nodded, found a place to sit down, and looked at Zhang Mu: "What's wrong?"

Zhang Mu said to Yu Shuangyong: "Lao Yu, let's talk about itYu Shuangyong nodded and took the data in his hand:

"That's it. We have extracted, separated, and purified the enzymes in the rat nervous system. We want to study in accordance with Professor Chen's original idea."

"Asparagine endopeptidase can modify Alzheimer’s tau protein to make it more toxic and adhesive. As you said, Parkinson’s disease is second only to Alzheimer’s disease. For neurodegenerative diseases, we also began to separate and purify the enzymes in Parkinson’s rats."

"But... it seems that we have encountered some problems. We don't know if it is due to technical reasons or other reasons. In this month, we have conducted more than 600 separations, more than 3,000 inspections, and tens of thousands of tests. No enzyme was found to make folded alpha-synuclein more toxic!"

"This is specific data. There are only 671 enzymes that we can find now, and we can't do it anymore!"

After Yu Shuangyong finished speaking, everyone sighed.

Taidanis couldn't help saying: "I found my friend Professor Considine, but... the other party doesn't seem to be willing to help us!"

Zhang Mu suddenly proposed: "Professor Chen, how about...Shall we change direction?"

Everyone nodded.

Since there is no way to study the asparagine endopeptidase of Alzheimer's disease in the field of enzymes, maybe we should change direction?

After all... Enzyme engineering is really expensive.

This month, Zhang Mu has invested nearly 30 million yuan in this field according to statistics.

This is scientific research, cruel and realistic!

Just when everyone was a little lost.

Chen Cang suddenly said, "How about...I will try?"

As soon as he said this, everyone around him became quiet.